As a Scientist - Viral Cell Line Development you will be involved in a range of internal platform development and commercial projects, primarily focusing on establishment of stable viral producer cell lines (suspension-based mammalian cell culture).
You will work as a technical lead to develop commercial service projects, autonomously planning and carrying out experimental work, but also collaborating closely with Group Leader, Project Manager and other colleagues to satisfy process requirements and delivery of desired outcome.
You will also be required to lead optimisation work for continuous improvement and to further increase throughput and efficiency of our Cell Line Development workflow.
As you become more competent with our processes, training and supervision of new staff and junior members will be expected to contribute to team’s and individual members’ continuous development.
The position will sit within the Viral Cell Line Development team working closely with the Viral Design and Discovery, Viral Manufacture, Process Development and Automation Team with focus on Lentivirus, rAAV and Adenoviral vectors.
The position will involve extensive interaction with both internal and external stakeholders and showing commitment to scientific development and innovation is considered essential.
- Lead and conduct Viral Cell Line Development commercial projects
- Contribute to project resourcing and timeline planning as well as day-to-day activity planning
- Support line manager with customer interactions, and in ensuring smooth running of the project
- Promote and suggest implementation of new methods, technologies and processes to improve current practice and develop new capabilities
- Support and lead new development and optimisation projects
- Carry out experiment design and planning, lab-bench work and data analysis
- Produce accurate records, data summary and reports
- Maintain lab facilities and equipment, take on responsibility as experienced user and support the team and Laboratory Manager as required
- Set an example to other colleagues, train and mentor junior staff
- Author and review Standard Operating Procedures and other quality related documents
- Support and contribute to protection and assessment of intellectual properties
- Keep up to date with the scientific literature and developments in the field
- MSc or PhD degree in Biotechnology, Cell and Molecular Biology, Biochemistry or other relevant degree
- Previous industry experience applicable to the role
- Prior experience of handling a range of adherent and suspension mammalian cell lines
- Good experience with analytical techniques including flow cytometry, qPCR and ELISA
- Highly detail-focused and quality-oriented mindset
- Good organisational and planning skills
- Development of stable mammalian cell lines: experience of cell sorting and characterisation of clonal cell lines
- Knowledge and experience of viral vector engineering, production and characterisation
- Molecular biology skills
- Use of robotic liquid handling and automation systems
- Experience with ISO 9001 Operating Quality System and familiar with GMP regulations
This advert will close as soon as sufficient applications have been received. Please submit your application as soon as possible to avoid missing the opportunity.
We have offices in the UK and USA. This role will be located at The Oxford Science Park, just 4 miles south east of Oxford, with parking and good public transport links from Oxford. Our UK office address is: Oxford Genetics Ltd, Robert Robinson Avenue, The Oxford Science Park, Oxford, OX4 4HG.
25 days annual leave plus UK Public holidays and a day off on your birthday; Pension with salary exchange and employer contribution; Group life cover; Employee assistance programme; Business travel insurance; Private medical insurance with great wellbeing benefits as a benefit in kind; Glasses Vouchers; Long service benefits including annual leave rising to 30 days; Oxford Science park free parking and a friendly working environment in an exciting and expanding company.
Our Oxford offices benefit from kitchen facilities on each floor with freshly ground coffee, tea, fruit juices, fruit and biscuits.
Culture: A chance to make a difference in a promotion-from-within environment; 2 whole company communication presentation events each year; social events including regular science presentations; regular TGIFriday events; Annual 2-day Staff Away Days; additional social committee events; and a commitment to quality, health and safety.
Environment: Modern offices and laboratories with a friendly working environment in a diverse and expanding company.
Values: Employee values include scientific excellence, ambition, diversity, teamwork and fun.
INFORMATION FOR INTERNATIONAL CANDIDATES
By the start of employment, the successful candidate must have, and be able to demonstrate, permission to work in the UK.
Unfortunately, as a small company, we have very limited ability to sponsor employees under Tier 2 (General) of the points based system, and we are unable to sponsor Tier 2 work visas for international graduates / candidates.